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Dermex NN Cream | 20gm
Dermex NN | Clobetasol Propionate + Neomycin Sulphate + Nystatin (0.5 mg+5 mg+1 Lac IU)/gm is prescribed for:
- Short-term treatment of stubborn eczema.
- Neurodermatoses.
- Psoriasis (except widespread plaque psoriasis) where secondary bacterial or fungal infections are present, suspected, or likely.
- Other inflammatory skin conditions are unresponsive to weaker corticosteroids.
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ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Dermex NN combines three active agents:
- Clobetasol Propionate: a very potent corticosteroid used to treat severe inflammatory skin conditions like eczema and psoriasis when weaker steroids are ineffective. Its main effect is reducing inflammation, partly through vasoconstriction and lowering collagen production.
- Neomycin Sulphate: an aminoglycoside antibiotic that works by binding to bacterial ribosomal subunits, disrupting protein synthesis, and causing errors in amino acid incorporation.
- Nystatin: an antifungal that binds to sterols in fungal cell membranes, altering permeability and leading to leakage of cell contents.
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✔️ Side Effects | Dermex NN Cream
Prolonged or extensive use may cause systemic absorption leading to hypercortisolism, especially in children or when used with occlusive dressings.
Long-term intensive use may cause skin thinning, stretch marks, visible blood vessel dilation, pigmentation changes, or increased hair growth.
✔️ Dosage & Administration | Dermex NN Cream
Adults: Apply sparingly to the affected area once or twice daily until symptoms improve. In resistant cases (e.g., with thickened skin), occlusion with plastic film may enhance results. Treatment should not exceed 7 days without medical supervision, and no more than 4 weeks without review.
Elderly: Safe for use, but caution is needed in renal impairment since systemic absorption of neomycin can occur.
Children (2+ years): Same dosing as adults. Not recommended in infants under 2 years due to increased absorption risk.
✔️ Interaction
- Neomycin, if significantly absorbed, may enhance respiratory depression caused by neuromuscular blockers.
- Systemic exposure is minimal if used correctly, making interactions unlikely.
- No harmful interactions reported with Clobetasol or Nystatin.
✔️ Not suitable for use in:
- Rosacea, acne vulgaris, perioral dermatitis.
- Primary viral skin infections (e.g., herpes simplex, chickenpox).
- Known hypersensitivity to any component of the preparation.
✔️ Pregnancy & Lactation
Neomycin can cross the placenta and may cause potential fetal toxicity.
Clobetasol's safety during breastfeeding has not been confirmed.
Use in pregnancy and lactation is generally not recommended.
✔️ Precautions & Warnings
- Avoid long-term continuous use, especially in children, due to the risk of adrenal suppression.
- Take care when applying near the eyes to prevent accidental entry, as this may cause glaucoma.
- If the cream/ointment enters the eye, rinse thoroughly with plenty of water.
✔️ Storage
- Store below 25°C.
- Do not freeze.
- Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
